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It's wonderful that you have had him for 11 years. Are you giving the meds directly into the mouth or are they in the water? When meds are in the water you can never be sure that the bird is actually ingesting enough to be effective in the treatment of a bacterial or fungal infection. One of my birds recently had a crop/ GI tract infection, the first 2 antibiotics were just not helping much so the vet did a culture to determine which antibiotic would be most effective against the particular bacteria, once we switched to a third antibiotic as indicated by the culture he began to improve, so sometimes meds have to be changed around until you get the most effective one.
 

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Why is a nebulizer being used in the treatment instead of giving medication directly into the mouth? What medication is in the nebulizer treatment?
 

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Megabacteria, a/k/a Avian Gastric Yeast (AGY) is actually a fungal infection that should be treated with amphotericin B, and the infection resides in the GI tract in the proventriculus and ventriculus. There are other fungal diseases such as Aspergillosis which is basically a respiratory disease. It is also possible that there is a secondary bacterial infection along with the AGY. The best way to determine if he has AGY is through a gram stain test on a crop swab or fresh dropping, although the organism does not always show up unless it is being actively shed.
 
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