Thank you for posting this link. The more data we can collect the better we will be able to respond to this issue effectively. Check out the references at the top of Illness and disease section Here on TB.
Amphoterracin B is currently the most effective but very expensive response to the fungal type organism, Megabacteria. There are homeopathic remedies, and other older antifungal treatments, But the Amphoterracin B is currently the best known and appears to be very effective but it is very expensive. Treating one bird is doable But a large flock is a big problem. Currently Sodium Benzoate is gaining in popularity across the globe because it is very cheap and you can purchase human grade on amazon in quantity for very reasonable cost.
There are now vets across the globe using it. We use Amphoteracin B in conjunction with Sodiun Benzoate. I also know breeders who have recovered the health of their flock using concentrated dose of Sodium Benzoate according to the Instructions listed in the Paper referenced and reprinted By
Sharman Hoppes,DVM at the Texas A & M university vet clinic in the Vet school school of medicine. and listed in a Sticky at the top of illness section here on TB.
The Megabacteria is often missed in the fecal exam as this organism seems to be passed in droppings intermittently. My bird did not show until the
organism was identified in the Necropsy done in speciality lab here in Georgia at the university of Georgia in Athens. So the best thing to do is have a campaign of clean environment, healthy food, and being alert to stressful situations your birds face. Cathy/Pretty Boy 's Budget is an example of being able to successfully catch and treat the Megabacteria before it has a chance to form a lethal attack on the organ systems of Your bird. The key here is to seek treatment ASAP when your budgie shows signs of illness. If left to linger in the bird, nothing your vet will be able to do when the birds body shuts down and it is no longer able to absorb nutrition through the GI tract. the Megabacteria attaches in the GI and blocks the absorption of nutrition. the result is usually seen as a radical loss of weight while the budgie seems to be eating like a little pig. Dropping often contain undigested seed. Typical signs of lethargy, fluffing, failure to sing/chirp are also general signs of other illnesses as well. Often The Megabac teams up with bacterial infections such that the bird will appear to get better and then reverse when the other organism attacks the immune system. It is hard to Diagnose. If untreated a budgie literally starves to death before your eyes. At some point untreated Megabac destroys the function of internal organs leading to mass organ system failure.
We Use Sodium Benzoate as a periodic prevention during weather that is conducive to the proliferation of Magabac and other fungal organisms. the hot muggy days of summer fit the bill perfectly here in Georgia. We do not give meds to chicks and breeding parents and families. In times of stress We start Electrolyte/probiotics alternating with ACV in drinking water and during
illness we soak millet spray in the electrolyte/probiotic water to encourage budgies who are off their food to eat. Recovery often hinges on getting your bird to eat and keep the little guys furnace going to keep it warm. A cold budgie is in trouble. When in doubt provide alternative heat in form of heat lamp, heat pad, pet snuggle, even a sock full of dry seeds and warmed in a microwave will work. Even a comfy snuggle on moms chest will help.
Best wishes, Jo Ann